Water → HCID 66702018, compound

Participants

Reaction Steps

N,N-Diisopropylethylamine (6.0 ml) was added to a solution of R-alaninol (12.0 ml) and 2-(benzylthio)-6-chloropyrimidin-4-amine (1.9 g) (Nugent, R. A., et al. PCT Int. Appl. 1996. 252 pp. WO9635678-A1) in NMP (6 ml) and stirred at 100° C. for three days before pouring into H2O (200 ml) and filtration of the precipitate. This solid was dried in vacuo to afford the subtitle compound as a pale sandy yellow solid. Yield: 4.1 g.

Provenance & Evidence