1-(Bromomethyl)-2,3-dichlorobenzene → HCID 136391541, compound

HRID 424666Notes

Reaction equation

HRID 424666 reaction equation
O.[NH2:2][C:3]1[CH:8]=[C:7]([OH:9])[N:6]=[C:5]([SH:10])[N:4]=1.[Cl:11][C:12]1[C:19]([Cl:20])=[CH:18][CH:17]=[CH:16][C:13]=1[CH2:14]Br>>[NH2:2][C:3]1[N:4]=[C:5]([S:10][CH2:14][C:13]2[CH:16]=[CH:17][CH:18]=[C:19]([Cl:20])[C:12]=2[Cl:11])[NH:6][C:7](=[O:9])[CH:8]=1

Participants

3

Reactant 2

HCID 27346021-(Bromomethyl)-2,3-dichlorobenzeneHCID 178507962HCID 178507962, compound

Product 1

HCID 136391541HCID 136391541, compound

Procedure

The subtitle compound was prepared according to the procedure of Example 1 step i) treating 4-amino-6-hydroxy-2-mercaptopyrimidine monohydrate (2.22 g) with 2,3-dichlorobenzyl bromide (3.30 g) to afford the subtitle compound as a white solid. Yield: 3.25 g.

Workup

  1. customThe subtitle compound was prepared

Sources & evidence

ORD record
ord-cf63185663bd44cbba65a00890e73e3c
Source dataset
uspto-grants-2012_01
Patent number
US08106063B2

Reaction notes

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