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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 424667Generated: October 29, 2026

m,alpha-Dichlorotoluene → 4-Amino-2-(3-chlorophenylmethylthio)-6-hydroxypyrimidine

https://huagongshe.com/reaction/424667

Reaction equation

Participants

RoleNameHCIDCharge
Reactantm,alpha-DichlorotolueneHCID 12103—
ReactantHCID 178507962HCID 178507962—
Product4-Amino-2-(3-chlorophenylmethylthio)-6-hydroxypyrimidineHCID 135427712—

Reaction Steps

The subtitle compound was prepared according to the procedure of Example 1 step i) treating 4-amino-6-hydroxy-2-mercaptopyrimidine monohydrate (10.00 g) with 3-chlorobenzyl chloride (9.98 g) to afford the subtitle compound as a white solid. Yield: 15.00 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106063B2
Source datasetuspto-grants-2012_01
ORD IDord-89c04bfe57524176ae897c385dc54249
Source noteuspto-grants-2012_01