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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 424998Generated: October 31, 2026

L-Prolinol → HCID 66703615, compound

https://huagongshe.com/reaction/424998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ProlinolHCID 640091—
Reactanterythro-N-Boc-D-phenylalanine epoxideHCID 11357515—
ProductHCID 66703615HCID 66703615—

Reaction Steps

Using general procedure 1 and purification method D with [(1R)-1-{(2R)-oxiran-2-yl}-2-phenyl-ethyl]carbamic acid tert-butylester (0.10 g, 0.38 mmol) and (2S)-2-hydroxymethyl-pyrrolidine (0.077 g, 0.76 mmol) gives the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106090B2
Source datasetuspto-grants-2012_01
ORD IDord-543eb62c523b442baedc0294cc3ac478
Source noteuspto-grants-2012_01