HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425068Generated: October 31, 2026
2,2,2-Trifluoroethanol → 2-(2,2,2-Trifluoroethoxy)ethan-1-ol
https://huagongshe.com/reaction/425068
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2,2,2-Trifluoroethanol | HCID 6409 | — |
| Reactant | Ethylene carbonate | HCID 7303 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | 2-(2,2,2-Trifluoroethoxy)ethan-1-ol | HCID 255854 | — |
Reaction Steps
2,2,2-trifluoroethanol (15 g), 1,3-dioxolan-2-one (19.8 g) and Et3N (15 g) were mixed together, and then the mixture was heated to 100° C. and stirred for 24 h. Then the reaction mixture was distilled to obtain intermediate BR (12.7 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08106021B2 |
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| Source dataset | uspto-grants-2012_01 |
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| ORD ID | ord-30655cb2a7d84943813024b34a828b71 |
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| Source note | uspto-grants-2012_01 |
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