HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 3-Chlorophenyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-Chlorophenol | HCID 7933 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Chlorophenyl acetate | HCID 83061 | — |
Reaction Steps
3-chlorophenol was dissolved in dichloromethane. Triethylamine (1 eq) and acetic anhydride (2 eq) were added. The mixture was stirred at room temperature for 5 hours. Solvent was eliminated by vacuum evaporation. The evaporation residue was taken up in dichloromethane, dried on magnesium sulfate and the solvent was eliminated by vacuum evaporation. Purification was carried out by chromatography on silica gel (elution:cyclohexane/ethyl acetate 95:5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106097B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-47a4d8daa42a4d05a544a60033f9c190 |
| Source note | uspto-grants-2012_01 |