tert-Butyl 2-bromo-2-methylpropionate → HCID 131727544, compound
Reaction equation
[CH2:1]([C:8]1[CH:13]=[CH:12][C:11]([C:14](=[O:36])[CH:15]=[CH:16][CH:17]2[C:22]([CH3:24])([CH3:23])[C:21]([CH3:25])=[C:20]([C:26]([O:28]C(C)(C)C)=[O:27])[C:19]([CH3:33])=[C:18]2[O:34][CH3:35])=[CH:10][CH:9]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].BrC(C)(C)C(OC(C)(C)C)=O>>[CH2:1]([C:8]1[CH:9]=[CH:10][C:11]([C:14](=[O:36])[CH:15]=[CH:16][CH:17]2[C:22]([CH3:23])([CH3:24])[C:21]([CH3:25])=[C:20]([C:26]([OH:28])=[O:27])[C:19]([CH3:33])=[C:18]2[O:34][CH3:35])=[CH:12][CH:13]=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7]Participants
3
Procedure
This compound was synthesized from 1-[4-heptylphenyl]-3-[3,5-dimethyl-4-tertbutyloxycarbonyldimethylmethyloxyphenyl]prop-2-en-1-one (compound 38) and tertbutyl bromoisobutyrate according to general method 4 described earlier.
Sources & evidence
- ORD record
- ord-d1afba48e22f493f8673d9922d43cf35
- Source dataset
- uspto-grants-2012_01
- Patent number
- US08106097B2
Reaction notes
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