Acetic Anhydride → HCID 22403906, compound

HRID 425257Notes

Reaction equation

HRID 425257 reaction equation
[NH2:1][C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:18])[CH:8]=2)[N:3]=1.[C:19](OC(=O)C)(=[O:21])[CH3:20]>>[C:19]([NH:1][C:2]1[CH:11]=[C:10]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([Cl:18])[CH:8]=2)[N:3]=1)(=[O:21])[CH3:20]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 672273HCID 672273, compound

Product 1

HCID 22403906HCID 22403906, compound

Conditions

Temperature
70 °C

Procedure

A mixture of 0.1 g of 2-amino-6-chloro-4-phenylquinoline and 8 ml of acetic anhydride was stirred at 70° C. for 1 hour, the solvent was removed by distillation, the solid residue was stirred with water, and the crystalline substance was filtered off.

Workup

  1. customthe solvent was removed by distillation
  2. stirringthe solid residue was stirred with water
  3. filtrationthe crystalline substance was filtered off

Sources & evidence

ORD record
ord-cccb3e67d18d4380b9c159108951512a
Source dataset
uspto-grants-2012_01
Patent number
US08106204B2

Reaction notes

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