HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sesamol → ethyl [4-bromo-3-hydroxy-3-(6-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sesamol | HCID 68289 | — |
| Reactant | 2,2-Dimethyl-2,3-dihydrobenzofuran-6-ol | HCID 20037293 | — |
| Reactant | ethyl (4-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate | HCID 28492473 | — |
| Reactant | 1-(2-cyclopropylethyl)-1H-indole-2,3-dione | HCID 65596570 | — |
| Product | ethyl [4-bromo-3-hydroxy-3-(6-hydroxy-2,2-dimethyl-2,3-dihydro-1-benzofuran-5-yl)-2-oxo-2,3-dihydro-1H-indol-1-yl]acetate | HCID 58872452 | — |
Reaction Steps
Following the procedure as described in PREPARATION 2B, and making non-critical variations to replace 1-(2-cyclopropylethyl)-1H-indole-2,3-dione with ethyl (4-bromo-2,3-dioxo-2,3-dihydro-1H-indol-1-yl)acetate and 1,3-benzodioxol-5-ol with 2,2-dimethyl-2,3-dihydrobenzofuran-6-ol, the title compound was obtained: MS (ES+) m/z 498.5 (M+23), 500.5 (M+23).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106087B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-75fd3969a9ab48b695d24b800d510154 |
| Source note | uspto-grants-2012_01 |