HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | 4-Bromophenol | HCID 7808 | — |
| Reactant | Sesamol | HCID 68289 | — |
| Reactant | 1-(2-cyclopropylethyl)-1H-indole-2,3-dione | HCID 65596570 | — |
| Product | 3-(5-bromo-2-hydroxyphenyl)-3-hydroxy-1,3-dihydro-2H-indol-2-one | HCID 12004333 | — |
Reaction Steps
Following the procedure as described in PREPARATION 2B, and making non-critical variations to replace 1-(2-cyclopropylethyl)-1H-indole-2,3-dione with isatin, 1,3-benzodioxol-5-ol with 4-bromophenol, the title compound was obtained (71%) as a yellowish solid: MS (ES+) m/z 319.4 (M+1), 321.4 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106087B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-f5b0375c2b154805a3c09dc6dc1f073a |
| Source note | uspto-grants-2012_01 |