HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 6-Chloropyridine-3-carbonyl chloride--hydrogen chloride (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Product | 6-Chloropyridine-3-carbonyl chloride--hydrogen chloride (1/1) | HCID 18548589 | 93% |
Reaction Steps
A solution of 6-chloronicotinic acid (10.00 g, 63.5 mmol) in SOCl2 (37 mL) was heated to reflux for 2 h. The SOCl2 was evaporated to dryness, to afford 12.56 g of the desired product (yield: 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536194B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-ca13c246ce1d4aa4be7ba99c5d23ee88 |
| Source note | uspto-grants-2013_09 |