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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425641Generated: October 29, 2026

ethyl (4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetate → (4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetic acid

https://huagongshe.com/reaction/425641

Reaction equation

Participants

RoleNameHCIDCharge
Reactantethyl (4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetateHCID 59263323—
Reactantethyl(2'-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-1'(2'H)-yl)acetateHCID 59263415—
Product(4'-bromo-6,6-dimethyl-2'-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-1'(2'H)-yl)acetic acidHCID 66642718—

Reaction Steps

Following the procedure as described in EXAMPLE 2, and making non-critical variations using ethyl (4′-bromo-6,6-dimethyl-2′-oxo-5,6-dihydrospiro[benzo[1,2-b:5,4-b′]difuran-3,3′-indol]-1′(2′H)-yl)acetate to replace ethyl (2′-oxospiro[furo[2,3-f][1,3]benzodioxole-7,3′-indol]-1′(2′H)-yl)acetate, the title compound was obtained. The product was used directly in the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106087B2
Source datasetuspto-grants-2012_01
ORD IDord-1575a53af5fd4267b92baaca63b19d7c
Source noteuspto-grants-2012_01