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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425671Generated: October 29, 2026

Cyclopropane, 1-(bromomethyl)-2-methyl- → HCID 59263350, compound

https://huagongshe.com/reaction/425671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropane, 1-(bromomethyl)-2-methyl-HCID 21891724—
Reactantspiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-oneHCID 53375495—
Reactant5,5-dimethyl-5,6-dihydrospiro[benzo[1,2-b:5,4-b']difuran-3,3'-indol]-2'(1H)-oneHCID 59263470—
ProductHCID 59263350HCID 59263350—

Reaction Steps

Following the procedure described in EXAMPLE 10.21, and making non-critical variations using spiro[furo[2,3-f][1,3]benzodioxole-7,3′-indol]-2′(1′H)one to replace 5,5-dimethyl-5,6-dihydrospiro[benzo[1,2-b:5,4-b′]difuran-3,3′-indol]-2′(1′H)-one, and 1-(bromomethyl)-2-methylcyclopropane to replace 2-(bromonmethyl)-5-(trifluoromethyl)furan, the title compound was obtained (37%) as a white solid: MS (ES+) m/z 350.3 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106087B2
Source datasetuspto-grants-2012_01
ORD IDord-f746d2ed0ff246fe919fa8004ca49f81
Source noteuspto-grants-2012_01