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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 42570Generated: October 29, 2026

Methyl iodide → 4,6-Bis(4-fluorophenyl)-1,3-dimethyl-5-(4-pyridyl)pyrazolo[3,4-b]pyridine

https://huagongshe.com/reaction/42570

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
Reactant4,6-Bis(4-fluorophenyl)-3-methyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridineHCID 178434376—
Product4,6-Bis(4-fluorophenyl)-1,3-dimethyl-5-(4-pyridyl)pyrazolo[3,4-b]pyridineHCID 68445847—

Reaction Steps

Following a similar procedure to that described in examples 6 and 7, but using 4,6-bis(4-fluorophenyl)-3-methyl-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 4) instead of 4,6-bis(4-fluorophenyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine and iodomethane instead of iodoethane, the title compounds were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08536194B2
Source datasetuspto-grants-2013_09
ORD IDord-919fd3d1026a4042aba47d4e6dbbcfc0
Source noteuspto-grants-2013_09