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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425789Generated: October 26, 2026

Thiourea → methyl 2-amino-5-(4-fluorophenyl)-1,3-thiazole-4-carboxylate

https://huagongshe.com/reaction/425789

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioureaHCID 2723790—
ReactantMethyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoateHCID 57437156—
Productmethyl 2-amino-5-(4-fluorophenyl)-1,3-thiazole-4-carboxylateHCID 2782963—

Reaction Steps

prepared by reaction of 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester with thiourea. LC-MS: tR=0.75 min; [M+H]+=253.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106215B2
Source datasetuspto-grants-2012_01
ORD IDord-2a2e31dfbe1d494cb5c968f25b8d5a12
Source noteuspto-grants-2012_01