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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425793Generated: October 30, 2026

HCID 66703722, compound → HCID 59411631, compound

https://huagongshe.com/reaction/425793

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66703722HCID 66703722—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 59411631HCID 59411631—

Reaction Steps

A solution of (1S,2S,5R)-2-(benzylamino-methyl)-3-aza-bicyclo[3.3.0]-octane-3-carboxylic acid tert.-butyl ester (354 mg) in EtOH (17 mL) was treated with Pd/C 10% (141 mg) and stirred under hydrogen (1 bar) for 16 h. After filtration through celite and removal of the solvents the title compound was obtained as an oil which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106215B2
Source datasetuspto-grants-2012_01
ORD IDord-8a1ec0ba5b514935bd2a0caeaef055be
Source noteuspto-grants-2012_01