2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid → HCID 25154185, compound

HRID 425808Notes

Reaction equation

HRID 425808 reaction equation
[C@H:1]12[CH2:8][CH2:7][CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:9][NH:10][C:11]([C:13]1[C:22]2[O:21][CH2:20][CH2:19][O:18][C:17]=2[CH:16]=[CH:15][CH:14]=1)=[O:12].[CH3:23][C:24]1[S:25][C:26]([C:32]2[CH:33]=[C:34]([CH3:38])[CH:35]=[CH:36][CH:37]=2)=[C:27]([C:29](O)=[O:30])[N:28]=1>>[CH3:23][C:24]1[S:25][C:26]([C:32]2[CH:33]=[C:34]([CH3:38])[CH:35]=[CH:36][CH:37]=2)=[C:27]([C:29]([N:3]2[CH2:4][C@H:5]3[C@H:1]([CH2:8][CH2:7][CH2:6]3)[C@H:2]2[CH2:9][NH:10][C:11]([C:13]2[C:22]3[O:21][CH2:20][CH2:19][O:18][C:17]=3[CH:16]=[CH:15][CH:14]=2)=[O:12])=[O:30])[N:28]=1

Participants

3

Reactant 2

HCID 532718162-Methyl-5-m-tolyl-thiazole-4-carboxylic acidHCID 59411635HCID 59411635, compound

Product 1

HCID 25154185HCID 25154185, compound

Procedure

prepared by reaction of 3,4-dihydro-benzo[1,4]dioxine-5-carboxylic acid-[(1S,2S,5R)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with 2-methyl-5-m-tolyl-thiazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-7f39908d5d6d4be39e80ce0198e82838
Source dataset
uspto-grants-2012_01
Patent number
US08106215B2

Reaction notes

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