2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid → HCID 25154333, compound

HRID 425811Notes

Reaction equation

HRID 425811 reaction equation
[CH3:1][CH:2]1[CH2:9][C@H:8]2[C@H:4]([CH2:5][NH:6][C@@H:7]2[CH2:10][NH:11][C:12]([C:14]2[C:23]3[O:22][CH2:21][CH2:20][O:19][C:18]=3[CH:17]=[CH:16][CH:15]=2)=[O:13])[CH2:3]1.[CH3:24][C:25]1[S:26][C:27]([C:33]2[CH:34]=[C:35]([CH3:39])[CH:36]=[CH:37][CH:38]=2)=[C:28]([C:30](O)=[O:31])[N:29]=1>>[CH3:1][CH:2]1[CH2:9][C@H:8]2[C@H:4]([CH2:5][N:6]([C:30]([C:28]3[N:29]=[C:25]([CH3:24])[S:26][C:27]=3[C:33]3[CH:34]=[C:35]([CH3:39])[CH:36]=[CH:37][CH:38]=3)=[O:31])[C@@H:7]2[CH2:10][NH:11][C:12]([C:14]2[C:23]3[O:22][CH2:21][CH2:20][O:19][C:18]=3[CH:17]=[CH:16][CH:15]=2)=[O:13])[CH2:3]1

Participants

3

Reactant 2

HCID 532718162-Methyl-5-m-tolyl-thiazole-4-carboxylic acidHCID 59411627HCID 59411627, compound

Product 1

HCID 25154333HCID 25154333, compound

Procedure

prepared by reaction of 3,4-dihydro-benzo[1,4]dioxine-5-carboxylic acid-[(1S,2S,5R)-7-methyl-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with 2-methyl-5-m-tolyl-thiazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-88fe48c3526e407c98d284c357be63f0
Source dataset
uspto-grants-2012_01
Patent number
US08106215B2

Reaction notes

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