2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid → HCID 25154334, compound
Reaction equation
[CH3:1][CH:2]1[CH2:9][C@H:8]2[C@H:4]([CH2:5][NH:6][C@@H:7]2[CH2:10][NH:11][C:12]([C:14]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:16]([CH3:23])[N:15]=2)=[O:13])[CH2:3]1.[CH3:24][C:25]1[S:26][C:27]([C:33]2[CH:34]=[C:35]([CH3:39])[CH:36]=[CH:37][CH:38]=2)=[C:28]([C:30](O)=[O:31])[N:29]=1>>[CH3:1][CH:2]1[CH2:9][C@H:8]2[C@H:4]([CH2:5][N:6]([C:30]([C:28]3[N:29]=[C:25]([CH3:24])[S:26][C:27]=3[C:33]3[CH:34]=[C:35]([CH3:39])[CH:36]=[CH:37][CH:38]=3)=[O:31])[C@@H:7]2[CH2:10][NH:11][C:12]([C:14]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:16]([CH3:23])[N:15]=2)=[O:13])[CH2:3]1Participants
3
Procedure
prepared by reaction of 1-methyl-1H-indazole-3-carboxylic acid-[(1S,2S,5R)-7-methyl-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with 2-methyl-5-m-tolyl-thiazole-4-carboxylic acid.
Sources & evidence
- ORD record
- ord-b162d8ff9ff84d70b5efa421f0d1d990
- Source dataset
- uspto-grants-2012_01
- Patent number
- US08106215B2
Reaction notes
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