2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid → HCID 25154377, compound

HRID 425817Notes

Reaction equation

HRID 425817 reaction equation
[C@H:1]12[CH2:8][CH2:7][CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:9][NH:10][C:11]([C:13]1[N:20]2[C:16]([S:17][CH:18]=[CH:19]2)=[N:15][CH:14]=1)=[O:12].[CH3:21][C:22]1[S:23][C:24]([C:30]2[CH:31]=[C:32]([CH3:36])[CH:33]=[CH:34][CH:35]=2)=[C:25]([C:27](O)=[O:28])[N:26]=1>>[CH3:21][C:22]1[S:23][C:24]([C:30]2[CH:31]=[C:32]([CH3:36])[CH:33]=[CH:34][CH:35]=2)=[C:25]([C:27]([N:3]2[CH2:4][C@H:5]3[C@H:1]([CH2:8][CH2:7][CH2:6]3)[C@H:2]2[CH2:9][NH:10][C:11]([C:13]2[N:20]3[C:16]([S:17][CH:18]=[CH:19]3)=[N:15][CH:14]=2)=[O:12])=[O:28])[N:26]=1

Participants

3

Reactant 2

HCID 532718162-Methyl-5-m-tolyl-thiazole-4-carboxylic acidHCID 59411608HCID 59411608, compound

Product 1

HCID 25154377HCID 25154377, compound

Procedure

prepared by reaction of imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with 2-methyl-5-m-tolyl-thiazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-052c0e9fddd54b029017583503d60430
Source dataset
uspto-grants-2012_01
Patent number
US08106215B2

Reaction notes

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