2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid → HCID 25154378, compound

HRID 425818Notes

Reaction equation

HRID 425818 reaction equation
[CH3:1][CH:2]1[CH2:9][C@H:8]2[C@H:4]([CH2:5][NH:6][C@@H:7]2[CH2:10][NH:11][C:12]([C:14]2[N:15]=[C:16]3[N:20]([CH:21]=2)[CH:19]=[CH:18][S:17]3)=[O:13])[CH2:3]1.[CH3:22][C:23]1[S:24][C:25]([C:31]2[CH:32]=[C:33]([CH3:37])[CH:34]=[CH:35][CH:36]=2)=[C:26]([C:28](O)=[O:29])[N:27]=1>>[CH3:1][CH:2]1[CH2:9][C@H:8]2[C@H:4]([CH2:5][N:6]([C:28]([C:26]3[N:27]=[C:23]([CH3:22])[S:24][C:25]=3[C:31]3[CH:32]=[C:33]([CH3:37])[CH:34]=[CH:35][CH:36]=3)=[O:29])[C@@H:7]2[CH2:10][NH:11][C:12]([C:14]2[N:15]=[C:16]3[N:20]([CH:21]=2)[CH:19]=[CH:18][S:17]3)=[O:13])[CH2:3]1

Participants

3

Reactant 2

HCID 532718162-Methyl-5-m-tolyl-thiazole-4-carboxylic acidHCID 59411605HCID 59411605, compound

Product 1

HCID 25154378HCID 25154378, compound

Procedure

prepared by reaction of imidazo[2,1-b]thiazole-6-carboxylic acid-[(1S,2S,5R)-7-methyl-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with 2-methyl-5-m-tolyl-thiazole-4-carboxylic acid.

Sources & evidence

ORD record
ord-0f19be626c754e43a9783162fc25edc3
Source dataset
uspto-grants-2012_01
Patent number
US08106215B2

Reaction notes

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