HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromobenzoic acid → (1S,2S,5R)-3-Bromo-N-[7-methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromobenzoic acid | HCID 11456 | — |
| Reactant | [(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone | HCID 59411601 | — |
| Product | (1S,2S,5R)-3-Bromo-N-[7-methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-benzamide | HCID 25154187 | — |
Reaction Steps
prepared by reaction of [(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 3-bromo-benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106215B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-90b5de5ab0c84fef8c5726264d852ea8 |
| Source note | uspto-grants-2012_01 |