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HRID 425831作成日：2026年10月25日

4-Methylpyridine-2-carboxylic acid → 4-Methyl-pyridine-2-carboxylic acid-(1S,2S,5R)-[7-methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide

https://huagongshe.com/reaction/425831

反応式

関与物質

役割名称HCID仕込み量
反応物4-Methylpyridine-2-carboxylic acidHCID 2762820—
反応物[(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanoneHCID 59411601—
生成物4-Methyl-pyridine-2-carboxylic acid-(1S,2S,5R)-[7-methyl-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amideHCID 25154264—

反応手順

prepared by reaction of [(1S,2S,5R)-2-aminomethyl-7-methyl-3-aza-bicyclo[3.3.0]oct-3-yl]-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 4-methyl-pyridine-2-carboxylic acid.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08106215B2
出典データセットuspto-grants-2012_01
ORD IDord-114cc1332d6d4b63a29c521fc05ce8d7
出典メモuspto-grants-2012_01