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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425859Generated: October 30, 2026

2-(3-methylphenyl)benzoic Acid → 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-(1S,2S,5R)-[7-methyl-3-(3'-methyl-biphenyl-2-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide

https://huagongshe.com/reaction/425859

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(3-methylphenyl)benzoic AcidHCID 4321321—
Reactant6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-7-methyl-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amideHCID 59411632—
Product6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-(1S,2S,5R)-[7-methyl-3-(3'-methyl-biphenyl-2-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amideHCID 25154583—

Reaction Steps

prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-7-methyl-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with commercially available 3′-methyl-biphenyl-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106215B2
Source datasetuspto-grants-2012_01
ORD IDord-90e921ffe57f437d93672c76037bf8bd
Source noteuspto-grants-2012_01