o-Phenylbenzoic acid → HCID 25154619, compound

HRID 425864Notes

Reaction equation

HRID 425864 reaction equation
[C@H:1]12[CH2:8][CH2:7][CH2:6][C@H:5]1[CH2:4][NH:3][C@@H:2]2[CH2:9][NH:10][C:11]([C:13]1[N:20]2[C:16]([S:17][CH:18]=[CH:19]2)=[N:15][C:14]=1[CH3:21])=[O:12].[C:22]1([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:23]([C:28](O)=[O:29])=[CH:24][CH:25]=[CH:26][CH:27]=1>>[C:22]1([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:23]([C:28]([N:3]2[CH2:4][C@H:5]3[C@H:1]([CH2:8][CH2:7][CH2:6]3)[C@H:2]2[CH2:9][NH:10][C:11]([C:13]2[N:20]3[C:16]([S:17][CH:18]=[CH:19]3)=[N:15][C:14]=2[CH3:21])=[O:12])=[O:29])=[CH:24][CH:25]=[CH:26][CH:27]=1

Participants

3

Reactant 2

HCID 70357o-Phenylbenzoic acidHCID 594116126-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide

Product 1

HCID 25154619HCID 25154619, compound

Procedure

prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with commercially available biphenyl-2-carboxylic acid.

Sources & evidence

ORD record
ord-d493a9fb6b62487f960253b8bbfd2d82
Source dataset
uspto-grants-2012_01
Patent number
US08106215B2

Reaction notes

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