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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425865Generated: October 26, 2026

2-(4-Fluorophenyl)benzoic acid → 6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-(1S,2S,5R)-[3-(4'-fluoro-biphenyl-2-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide

https://huagongshe.com/reaction/425865

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Fluorophenyl)benzoic acidHCID 2782687—
Reactant6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amideHCID 59411612—
Product6-Methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-(1S,2S,5R)-[3-(4'-fluoro-biphenyl-2-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amideHCID 25154657—

Reaction Steps

prepared by reaction of 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid-[(1S,2S,5R)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide with commercially available 4′-fluoro-biphenyl-2-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106215B2
Source datasetuspto-grants-2012_01
ORD IDord-5f77b58c95ff42289b7c7448a7f85a7d
Source noteuspto-grants-2012_01