HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazo(1,2-a)pyridine-3-carboxylic acid → Imidazo[1,2-a]pyridine-3-carboxylic acid-(1S,2S,5R)-[7,7-difluoro-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazo(1,2-a)pyridine-3-carboxylic acid | HCID 73142 | — |
| Reactant | (1S,2S,5R)-(2-aminomethyl-7,7-difluoro-3-aza-bicyclo[3.3.0]-oct-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone | HCID 59411607 | — |
| Product | Imidazo[1,2-a]pyridine-3-carboxylic acid-(1S,2S,5R)-[7,7-difluoro-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide | HCID 25154190 | — |
Reaction Steps
prepared by reaction of (1S,2S,5R)-(2-aminomethyl-7,7-difluoro-3-aza-bicyclo[3.3.0]-oct-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with imidazo[1,2-a]pyridine-3-carboxylic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106215B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-2debcf120e724c3bb058962e7bf3f486 |
| Source note | uspto-grants-2012_01 |