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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425882Generated: October 26, 2026

1H-Indazole-3-carboxylic acid, 1-methyl- → 1-Methyl-1H-indazole-3-carboxylic acid-(1S,2S,5R)-[7,7-difluoro-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amide

https://huagongshe.com/reaction/425882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indazole-3-carboxylic acid, 1-methyl-HCID 689105—
Reactant(1S,2S,5R)-(2-aminomethyl-7,7-difluoro-3-aza-bicyclo[3.3.0]-oct-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanoneHCID 59411607—
Product1-Methyl-1H-indazole-3-carboxylic acid-(1S,2S,5R)-[7,7-difluoro-3-(2-methyl-5-m-tolyl-thiazole-4-carbonyl)-3-aza-bicyclo[3.3.0]oct-2-ylmethyl]-amideHCID 25154191—

Reaction Steps

prepared by reaction of (1S,2S,5R)-(2-aminomethyl-7,7-difluoro-3-aza-bicyclo[3.3.0]-oct-3-yl)-(2-methyl-5-m-tolyl-thiazol-4-yl)-methanone with 1-methyl-1H-indazole-3-carboxylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106215B2
Source datasetuspto-grants-2012_01
ORD IDord-7353caf0ec4446e9bbe1156464bb872c
Source noteuspto-grants-2012_01