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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425915Generated: October 30, 2026

2-Amino-3,5-dibromopyrazine → 5-Bromo-3-[1-(2-chloro-3,6-difluoro-phenyl)-ethoxy]-pyrazin-2-ylamine

https://huagongshe.com/reaction/425915

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-3,5-dibromopyrazineHCID 620004—
Reactant2-Chloro-3,6-difluoro-α-methylbenzenemethanolHCID 21111374—
Product5-Bromo-3-[1-(2-chloro-3,6-difluoro-phenyl)-ethoxy]-pyrazin-2-ylamineHCID 21111482—

Reaction Steps

5-bromo-3-[1-(2-chloro-3,6-difluoro-phenyl)-ethoxy]-pyrazin-2-ylamine was prepared following procedure 2 from 1-(2-chloro-3,6-difluoro-phenyl)-ethanol and 3,5-dibromo-pyrazin-2-ylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106197B2
Source datasetuspto-grants-2012_01
ORD IDord-a8aa89d2fec94a62aca6e45007c2ac0a
Source noteuspto-grants-2012_01