2-Amino-3,5-dibromopyrazine → HCID 21111481, compound

HRID 425916Notes

Reaction equation

HRID 425916 reaction equation
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[C:4]([F:9])[C:3]=1[CH:10]([OH:14])[CH:11]([CH3:13])[CH3:12].Br[C:16]1[C:17]([NH2:23])=[N:18][CH:19]=[C:20]([Br:22])[N:21]=1>>[Br:22][C:20]1[N:21]=[C:16]([O:14][CH:10]([C:3]2[C:4]([F:9])=[CH:5][CH:6]=[C:7]([F:8])[C:2]=2[Cl:1])[CH:11]([CH3:12])[CH3:13])[C:17]([NH2:23])=[N:18][CH:19]=1

Participants

3

Reactant 2

HCID 6200042-Amino-3,5-dibromopyrazineHCID 21111373HCID 21111373, compound

Product 1

HCID 21111481HCID 21111481, compound

Procedure

5-bromo-3-[1-(2-chloro-3,6-difluoro-phenyl)-2-methyl-propoxy]-pyrazin-2-ylamine was prepared following procedure 2 from 1-(2-chloro-3,6-difluoro-phenyl)-2-methyl-propan-1-ol and 3,5-dibromo-pyrazin-2-ylamine.

Sources & evidence

ORD record
ord-cc14a1d1fdf74edf91bfc6cd9a9660e4
Source dataset
uspto-grants-2012_01
Patent number
US08106197B2

Reaction notes

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