2-Amino-3,5-dibromopyrazine → HCID 21111477, compound

HRID 425918Notes

Reaction equation

HRID 425918 reaction equation
[Cl:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[C:4]([Cl:9])[C:3]=1[CH:10]([OH:12])[CH3:11].Br[C:14]1[C:15]([NH2:21])=[N:16][CH:17]=[C:18]([Br:20])[N:19]=1>>[Br:20][C:18]1[N:19]=[C:14]([O:12][CH:10]([C:3]2[C:4]([Cl:9])=[CH:5][CH:6]=[C:7]([F:8])[C:2]=2[Cl:1])[CH3:11])[C:15]([NH2:21])=[N:16][CH:17]=1

Participants

3

Reactant 2

HCID 6200042-Amino-3,5-dibromopyrazineHCID 167700681-(2,6-Dichloro-3-fluorophenyl)ethan-1-ol

Product 1

HCID 21111477HCID 21111477, compound

Procedure

5-Bromo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyrazin-2-ylamine was prepared following procedure 2 from 1-(2,6-dichloro-3-fluoro-phenyl)-ethanol and 3,5-dibromo-pyrazin-2-ylamine.

Sources & evidence

ORD record
ord-51acdf88e63347c790110811f43e838f
Source dataset
uspto-grants-2012_01
Patent number
US08106197B2

Reaction notes

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