Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(2-Morpholin-4-ylethoxy)benzeneboronic acid, pinacol ester → 3-(2,6-Dichloro-benzyloxy)-5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-pyridin-2-ylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(2-Morpholin-4-ylethoxy)benzeneboronic acid, pinacol ester | HCID 4625910 | — |
| 반응물 | 3-(2,6-Dichlorobenzyloxy)-5-bromopyridin-2-amine | HCID 21111487 | — |
| 생성물 | 3-(2,6-Dichloro-benzyloxy)-5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-pyridin-2-ylamine | HCID 10254297 | — |
반응 단계
3-(2,6-Dichloro-benzyloxy)-5-[4-(2-morpholin-4-yl-ethoxy)-phenyl]-pyridin-2-ylamine was prepared from 5-bromo-3-(2,6-dichloro-benzyloxy)-pyridin-2-ylamine (example I(a)) and 4-{2-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-ethyl}-morpholine (prepared in part 1) following procedure 3 as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08106197B2 |
| 출처 데이터셋 | uspto-grants-2012_01 |
| ORD ID | ord-f3fd9ab8870d4a6aa11bd87ef76578f7 |
| 출처 메모 | uspto-grants-2012_01 |