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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425938Generated: October 30, 2026

N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamide → N-{4-[6-Amino-5-(2-cyano-benzyloxy)-pyridin-3-yl]-phenyl}-methanesulfonamide

https://huagongshe.com/reaction/425938

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanesulfonamideHCID 16217653—
Reactant2-(2-Amino-5-bromo-pyridin-3-yloxymethyl)-benzonitrileHCID 21111380—
ProductN-{4-[6-Amino-5-(2-cyano-benzyloxy)-pyridin-3-yl]-phenyl}-methanesulfonamideHCID 21111366—

Reaction Steps

N-{4-[6-Amino-5-(2-cyano-benzyloxy)-pyridin-3-yl]-phenyl}-methanesulfonamide was prepared following procedure 3 from 2-(2-Amino-5-bromo-pyridin-3-yloxymethyl)-benzonitrile and N-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-methanesulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106197B2
Source datasetuspto-grants-2012_01
ORD IDord-30f7e8b22988416abd66a347b024fcc0
Source noteuspto-grants-2012_01