HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 425959Generated: October 25, 2026
Cyclopentylamine → 4-Chloro-2-(cyclopentylamino)benzonitrile
https://huagongshe.com/reaction/425959
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cyclopentylamine | HCID 2906 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Chloro-2-fluorobenzonitrile | HCID 93655 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Chloro-2-(cyclopentylamino)benzonitrile | HCID 43681510 | — |
Reaction Steps
Cyclopentylamine and potassium carbonate were added to a DMF solution of 4-chloro-2-fluorobenzonitrile, followed by stirring at 100° C. for 12 hours. By post-treating the reaction liquid, 4-chloro-2-(cyclopentylamino)benzonitrile was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08106190B2 |
|---|
| Source dataset | uspto-grants-2012_01 |
|---|
| ORD ID | ord-5f11b7f2f9c34c1c822d468a41e92ad5 |
|---|
| Source note | uspto-grants-2012_01 |
|---|
