HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 66704562, compound → HCID 59364335, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 66704562 | HCID 66704562 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | HCID 59364335 | HCID 59364335 | 143.8% |
Reaction Steps
tert-butyl 3-(2-(methoxycarbonyl)aminoethoxy)-3-(2-methyl-5-chlorophenyl)propyl(methyl)carbamate (110 mg) was dissolved in a solution of 20% (V/V) TFA/CH2Cl2 (10 mL). The reaction mixture was stirred at room temperature for 1 h. The reaction mixture was concentrated in vacuo to afford methyl 2-(1-(5-chloro-2-methylphenyl)-3-(methylamino)propoxy)ethylcarbamate (120 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08106221B2 |
| Source dataset | uspto-grants-2012_01 |
| ORD ID | ord-d23ac87b94a34d33ad59c4116f672bf0 |
| Source note | uspto-grants-2012_01 |