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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 426044Generated: October 30, 2026

HCID 66704562, compound → HCID 59364335, compound

https://huagongshe.com/reaction/426044

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66704562HCID 66704562—
SolventTrifluoroacetic acid methylene chlorideHCID 21863450—
ProductHCID 59364335HCID 59364335143.8%

Reaction Steps

tert-butyl 3-(2-(methoxycarbonyl)aminoethoxy)-3-(2-methyl-5-chlorophenyl)propyl(methyl)carbamate (110 mg) was dissolved in a solution of 20% (V/V) TFA/CH2Cl2 (10 mL). The reaction mixture was stirred at room temperature for 1 h. The reaction mixture was concentrated in vacuo to afford methyl 2-(1-(5-chloro-2-methylphenyl)-3-(methylamino)propoxy)ethylcarbamate (120 mg, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106221B2
Source datasetuspto-grants-2012_01
ORD IDord-d23ac87b94a34d33ad59c4116f672bf0
Source noteuspto-grants-2012_01