HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl chloroformate → N-Benzyloxycarbonyl-[5-(2-methylsulfanylpyrimidin-4-yl)-6-(3-trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl chloroformate | HCID 10387 | — |
| Reactant | HCID 178503412 | HCID 178503412 | — |
| Product | N-Benzyloxycarbonyl-[5-(2-methylsulfanylpyrimidin-4-yl)-6-(3-trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]amine | HCID 68446171 | — |
Reaction Steps
Following a similar procedure to that described in example 245, but starting from 3-amino-5-[2-(methylsulfanyl)pyrimidin-4-yl]-6-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine (obtained in example 123) and benzyl chloroformate, the desired compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536194B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-be303c740c6b418980d029423d371008 |
| Source note | uspto-grants-2013_09 |