HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nicotinic Acid → 3-Pyridinecarbonyl chloride, hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nicotinic Acid | HCID 938 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Product | 3-Pyridinecarbonyl chloride, hydrochloride (1:1) | HCID 88438 | — |
Reaction Steps
A solution of nicotinic acid (0.50 g, 4.0 mmol) and POCl3 (5 mL) was heated at reflux for 1.5 h and concentrated. The product obtained was directly used in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536194B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-d0bbcd6f753245b1a3784a550e794017 |
| Source note | uspto-grants-2013_09 |