HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nicotinoyl chloride → N-[2-[4,6-Bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridin-2-yl]ethyl]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nicotinoyl chloride | HCID 82604 | — |
| Reactant | 2-(2-Aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine | HCID 67013573 | — |
| Product | N-[2-[4,6-Bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridin-2-yl]ethyl]nicotinamide | HCID 68443044 | — |
Reaction Steps
Following a similar procedure to that described in example 245, but starting from 2-(2-aminoethyl)-4,6-bis(4-fluorophenyl)-5-(4-pyridyl)pyrazolo[3,4-b]pyridine (obtained in example 90) and nicotinoyl chloride hydrichloride (obtained in section a), the title compound was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08536194B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-439100f92aaa42f8bbff90d066c8829a |
| Source note | uspto-grants-2013_09 |