2-(3-Bromopropoxy)tetrahydro-2H-pyran → 6-(4-Fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-2-[3-(tetrahydropyran-2-yloxy)propyl]pyrazolo[3,4-b]pyridine

Participants

Role	Name	HCID	Charge
Reactant	2-(3-Bromopropoxy)tetrahydro-2H-pyran	HCID 2777988	—
Reactant	6-(4-fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine	HCID 67014974	—
Product	6-(4-Fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-2-[3-(tetrahydropyran-2-yloxy)propyl]pyrazolo[3,4-b]pyridine	HCID 68444458	—

Reaction Steps

Following a similar procedure to that described in examples 6 and 7, but starting from 6-(4-fluorophenyl)-4-(2-furyl)-5-(4-pyridyl)-1H-pyrazolo[3,4-b]pyridine (obtained in example 171) and 2-(3-bromopropoxy)tetrahydropyran, the desired compound was obtained.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08536194B2
Source dataset	uspto-grants-2013_09
ORD ID	ord-8f37a0f7fc454d6eb93760b202ce5b41
Source note	uspto-grants-2013_09