Potassium Carbonate → HCID 59184842, compound

Participants

Reaction Steps

Potassium carbonate (25 mg, 0.18 mmol) and lithium chloride (24 mg, 0.18 mmol) were added to a solution of N-(3-cyano-5-methyl-phenyl)-N-(5-isopropyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-4-yl)-acetamide (60 mg, 0.18 mmol) and (4-bromomethyl-6-fluoro-pyridin-2-yl)-(4-methoxy-benzyl)-amine (59 mg, 0.18 mmol) in dimethylformamide (1 mL). After 17 hours the solvent was removed and the residue was subjected to flash chromatography (eluant: 0-5% methanol/dichloromethane). The product containing fractions were combined and the solvent was removed in vacuo to yield the product (58 mg, 0.10 mmol). C31H31FN6O4 calculated 570.2, observed [M+1]+ 571.1; rt=3.82 min.

Provenance & Evidence