3,5-Bis-trifluoromethylphenylboronic acid → 4-Methyl-2-(5-trifluoromethanesulfonyloxy-3',5'-bis-trifluoromethyl-bi phenyl-3-yl)-pentanoic acid methyl ester

Participants

Reaction Steps

The title compound was prepared in 71% yield from 2-(3-benzyloxy-5-trifluoromethanesulfonyloxy-phenyl)-4-methyl-pent-4-enoic acid methyl ester (prepared in Example 26, step (c)) under the conditions described in Example 26, step (d-f)) using 3,5-bis-trifluoromethylphenylboronic acid in step (d).

Provenance & Evidence