3,5-Bis-trifluoromethylphenylboronic acid → 2-(3,5-Bis-trifluoromethyl-4''-chloro-3''-trifluoromethyl-[1,1';3',1'']terphenyl-5'-yl)-4-methyl-pentanoic acid methyl ester

Participants

Reaction Steps

The title compound was prepared in 50% yield from 2-(4′-chloro-5-trifluoromethanesulfonyloxy-3′-trifluoromethyl-biphenyl-3-yl)-4-methyl-pentanoic acid methyl ester (prepared in Intermediate C) and 3,5-bis-trifluoromethylphenylboronic acid under the conditions described in Example 26, step (d).

Provenance & Evidence