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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 426364Generated: October 31, 2026

(S)-4-Benzyl-2-oxazolidinone → 4-Benzyl-3-[2-(5-benzyloxy-4'-trifluoromethyl-biphenyl-3-yl)-acetyl]-oxazolidin-2-one

https://huagongshe.com/reaction/426364

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-4-Benzyl-2-oxazolidinoneHCID 736225—
Reactant(5-Benzyloxy-4'-trifluoromethyl-biphenyl-3-yl)-acetic acidHCID 11501912—
Product4-Benzyl-3-[2-(5-benzyloxy-4'-trifluoromethyl-biphenyl-3-yl)-acetyl]-oxazolidin-2-oneHCID 66698236—

Reaction Steps

The title compound was prepared from (5-benzyloxy-4′-trifluoromethyl-biphenyl-3-yl)-acetic acid and (S)-(−)-4-benzyl-2-oxazolidinone following the same procedure as for the synthesis of compound 39a.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08106236B2
Source datasetuspto-grants-2012_01
ORD IDord-bec6bbfac35c4691bfac30da23f3cf39
Source noteuspto-grants-2012_01