2-(Ethylthio)ethanol → Ethylmercaptoethyl 2-[4-(4-chlorophenoxy-methyl)-phenoxy]-propionate

Participants

Reaction Conditions

Reaction Steps

A mixture consisting of 6.4 gm of methyl 2-[4-(4-chlorophenoxy-methyl)-phenoxy]-propionate and 2.12 gm of 2-ethylmercapto-ethanol was heated to 100° C. on an oil bath, 0.02 gm of sodium was added to the hot mixture, and it was then heated at 150° C. for five hours, the pressure being periodically reduced to 150 mm Hg. Thereafter, the reaction product was isolated as an oil, yielding 6.0 gm (76% of theory) of the ester named in the heading.

Provenance & Evidence