反应详情

3 g of thionyl bromide was added dropwise with stirring to 2.0 g (10.3 mmoles) of 1-carboxytricyclo[4.3.1.12,5 ]undecane dissolved in 20 ml of anhydrous benzene at room temperature. The mixture was heated under reflux for 1.5 hours. After cooling, the excess thionyl bromide and benzene were distilled off under reduced pressure. The residue obtained was distilled under reduced pressure to afford 2.0 g (yield: 75.5%) of 1-bromocarbonyltricyclo[4.3.1.12,5 ]undecane having a boiling point of 116° C. (1 mmHg).

1. temperatureThe mixture was heated
2. temperatureunder reflux for 1.5 hours
3. temperatureAfter cooling
4. distillationthe excess thionyl bromide and benzene were distilled off under reduced pressure
5. customThe residue obtained
6. distillationwas distilled under reduced pressure