HCID 20389816, compound → HCID 178504116, compound

HRID 426713Notes

Reaction equation

HRID 426713 reaction equation
COC1C(OC)=C(OC)C=C([N+]([O-])=O)C=1Br.[ClH:17].[CH3:18][SH:19]1(=[O:48])[C:24]2[C:25](OC)=[C:26]([O:31][CH3:32])[C:27]([O:29]C)=[CH:28][C:23]=2[N:22]=[C:21]([N:35]2[CH2:40][CH2:39][N:38]([C:41]([C:43]3[O:44][CH:45]=[CH:46][CH:47]=3)=[O:42])[CH2:37][CH2:36]2)[NH:20]1>>[ClH:17].[CH3:18][SH:19]1(=[O:48])[C:24]2[CH:25]=[C:26]3[O:31][CH2:32][O:29][C:27]3=[CH:28][C:23]=2[N:22]=[C:21]([N:35]2[CH2:36][CH2:37][N:38]([C:41]([C:43]3[O:44][CH:45]=[CH:46][CH:47]=3)=[O:42])[CH2:39][CH2:40]2)[NH:20]1

Participants

3

Reactant 2

HCID 20389816HCID 20389816, compoundHCID 178486693HCID 178486693, compound

Product 1

HCID 178504116HCID 178504116, compound

Procedure

By employing 2,3,4-trimethoxy-6-nitrophenylbromide as a starting material, and following the procedures of the above examples, 1-methyl-3-[4-(2-furoyl)-piperazino]-6,7,8-trimethoxy-1H-1,2,4-benzothiadiazine-1-oxide hydrochloride was prepared. The compound melted at 130°-2° C.

Workup

  1. customwas prepared

Sources & evidence

ORD record
ord-a6a125040e7a42bca52b78c8cfd4ab7f
Source dataset
uspto-grants-1979_10
Patent number
US04171361

Reaction notes

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