4-Toluenesulfonyl chloride → HCID 86736662, compound

Participants

Reaction Steps

Dissolve 10 gm. of the alcohol and 15.4 gm. of tosyl chloride in 100 ml. of dry pyridine and let the solution stand at 25°C. for 17 hours. Add ethanol and evaporate the solution to a residue and then azeotrope with toluene. Chromatograph the residue on a silica gel column (110 × 2.5 cm) using 10% acetone in hexane as the eluant to obtain 4-deoxy-6O-tosyl-D-threo-hex-1-enopyranose.

Provenance & Evidence