Ethylenediamine → HCID 12763855, compound

Participants

Reaction Steps

N[1-(3-methylbutyl)-3-methyl-5-pyrazolyl]-S-methyl isothiourea hydroiodide (29.0 g.) was suspended in 160 ml. n-propyl alcohol. Ethylene diamine (10.2 g.) was added and the solution was refluxed 18 hrs. The solvent was concentrated in vacuum and the residue was treated with KHCO3 in water. The resulting solid was recrystallized from CHCl3 -ether mixtures to obtain 14.3 g. product, mp 104°-106° C.

Provenance & Evidence