HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 5,8-Difluoro-1,4-benzodioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-(2,3,6-Trifluorophenoxy)ethanol | HCID 2777944 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5,8-Difluoro-1,4-benzodioxane | HCID 4464242 | — |
Reaction Steps
2-(2,3,6-Trifluorophenoxy) ethanol (48.8 g, 0.254 mole) and 24 g of anhydrous potassium carbonate in 800 ml of dimethylformamide was refluxed for 20 hours and then poured into water. This was extracted with ether, washed with water, and dried to give 5,8-difluoro-1,4-benzodioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04171359 |
| Source dataset | uspto-grants-1979_10 |
| ORD ID | ord-f8ca3c9a2c7248d7b8e319529edd37db |
| Source note | uspto-grants-1979_10 |