(2-Methyl-3-amino-5-ethyl-phenyl)-benzyl ether → (3-Acetamino-2,5-dimethyl-phenyl)-benzyl ether

HRID 426839Notes

Reaction equation

HRID 426839 reaction equation
[CH3:1][C:2]1[C:7]([NH:8][C:9]([CH3:11])=[O:10])=[CH:6][C:5]([CH2:12]C)=[CH:4][C:3]=1[O:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.CC1C([N+]([O-])=O)=CC(CC)=CC=1OCC1C=CC=CC=1.CC1C(N)=CC(CC)=CC=1OCC1C=CC=CC=1.C(N1C2C(=C(OCC3C=CC=CC=3)C=C(CC)C=2)C=N1)(=O)C>>[NH:8]([C:7]1[C:2]([CH3:1])=[C:3]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH:4]=[C:5]([CH3:12])[CH:6]=1)[C:9]([CH3:11])=[O:10]

Participants

5

Reactant 4

HCID 20390198(2-Methyl-3-amino-5-ethyl-phenyl)-benzyl etherHCID 203902011-Acetyl-4-benzyloxy-6-ethyl-indazoleHCID 20390202(2-Methyl-3-nitro-5-ethyl-phenyl)-benzyl etherHCID 70602826(2-Methyl-3-acetamino-5-ethyl-phenyl)-benzyl ether

Product 1

HCID 70601315(3-Acetamino-2,5-dimethyl-phenyl)-benzyl ether

Procedure

from (2-methyl-3-acetamino-5-ethyl-phenyl)-benzyl ether; m.p. 139°-140° C. (prepared via (2-methyl-3-nitro-5-ethyl-phenyl)-benzyl ether and (2-methyl-3-amino-5-ethyl-phenyl)-benzyl ether), 1-acetyl-4-benzyloxy-6-ethyl-indazole; m.p. 109,5°-110,5° C.

Sources & evidence

ORD record
ord-8ba557b13789477fb9f0a6467667bc17
Source dataset
uspto-grants-1979_10
Patent number
US04171446

Reaction notes

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